Charles and Anna ran a store in Hedwig's Hill, dealing in the basic necessities of frontier life, including wool, cotton, cattle, hogs, and sheep, which no respectable farm could do without. But in 1864, Charles fell ill with rheumatism, a common affliction in the 19th century, and was bedridden until his death in 1879. Even without Charles' illness, the Martins were in dire straights. With the nearby Fort Mason abandoned during the Civil War, local banditry was on the uptick. The store was the frequent target of lootings and had endured repeated attacks by local confederates who resented the Martin's Union sympathies. To add insult to injury, the Confederate dollar, which the Martins had no choice but to accept, had become worthless after the war. The Martins were penniless, and Anna, who was only 21 at the time, had no choice but to eventually commandeer her husband's business affairs. Source.
But then a funny thing happened, funny at least for how exceptional it was at the time: Anna found herself to be quite the savvy businesswoman, foreseeing, for example, the eventual supremacy of barbed wire on the ranch. (Her store was the first to carry it in Mason County.) Over time, along with her sons, Anna developed their family's freighting business and by the 1890s, her name was appearing in papers alongside cattleman like J. W. White. In 1893, major Texas newspaper the Galveston Daily News reported that Martin had shipped "thirty carloads of cattle to Chicago," (September 30, 1893). You don't have to know much about cattle to know that 30 carloads is nothing to sneeze at.